USAF A-8564
3,3'-iminodipropiononitrile
CAS: 111-94-4
Molecular Formula: C6H9N3
USAF A-8564 - Names and Identifiers
USAF A-8564 - Physico-chemical Properties
| Molecular Formula | C6H9N3 |
| Molar Mass | 123.16 |
| Density | 1.02g/mLat 25°C(lit.) |
| Melting Point | -6 °C |
| Boling Point | 205°C25mm Hg(lit.) |
| Flash Point | >230°F |
| Water Solubility | Soluble in water. |
| Vapor Presure | 0.00019mmHg at 25°C |
| pKa | 6.13±0.19(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable, but moisture sensitive. Reaction with moisture may lead to a build up of pressure in sealed bottles. Combustible. Incompatible with strong oxidizing agents. |
| Refractive Index | n20/D 1.47(lit.) |
USAF A-8564 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | UN 3334 |
| WGK Germany | 2 |
| RTECS | UG2975000 |
| TSCA | Yes |
| HS Code | 29269095 |
| Toxicity | A neurotoxic synthetic nitrile that causes proximal axonopathies in the spinal cord and brain stem. The proximal axonal swellings are due to interruption of slow axonal transport, resulting in a large accumulation of neurofilaments. Secondary to these effects is a progressive atrophy of the distal axon, secondary demyelination, and gliosis. The slow axonal transport defect appears to be selective, as little evidence for perturbations in fast axonal transport have been reported. Behaviorally, IDPN induces hyperactivity, a “waltzing syndrome,” circling and head-rolling in mice and rats. IDPN intoxication has been advanced as a model for certain motor neuron degenerative diseases such as amyotropic lateral sclerosis (ALS) and hereditary canine spinal muscular atrophy (HCSMA). |
USAF A-8564 - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| category | toxic substances |
| toxicity classification | poisoning |
| acute toxicity | oral administration-rat LD50: 2700 mg/kg; Abdominal cavity-mouse LD50: 200 mg/kg |
| stimulation data | skin-rabbit 500 mg/24 hours mild; Eye-rabbit 500 mg severe |
| explosive hazard characteristics | explosive storage in sealed container |
| flammability hazard characteristics | combustible; combustion produces toxic nitrogen oxides and cyanide smoke |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; Separate storage and transportation from food and oxidant; Pay attention to package tightness |
| fire extinguishing agent | mist water, foam, carbon dioxide |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-10 22:29:15
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